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March 1963

The Exocrine Pancreas: Normal and Abnormal Functions.

Am J Dis Child. 1963;105(3):320-321. doi:10.1001/archpedi.1963.02080040322026

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In this Ciba Foundation Symposium monograph the fine structure of the exocrine pancreas as visualized by electron microscope and light microscope is presented, including 11 excellent illustrations of the former. The pancreatic enzymes, fluid, and electrolytes are discussed, particularly regarding the influence of diet and gastrointestinal hormones. Pancreatic juice studies are applied to clinical assessment of pancreatic function.

For evaluation of pancreatic deficiency, the amino acid absorption test is favored by Vink. According to this discussant, the sweat test in diagnosis of cystic fibrosis is more significant in children than in adults. Stimulation by local iontophoresis is the preferred technique for this.

Studies of the phospholipid effect, namely, evidence of phospholipid turnover under stimulation by acetylcholine, in pancreas tissue slices is mentioned by Hokin and Hokin. Such studies involved microradioautography with P32 and H2 inositol. Allusion is made to the phospholipid effect in the avian salt gland and

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