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June 1963

VI. Detection of Implanted Staphylococcus Aureus Strain: Use of Serological and Phage Typing

Author Affiliations

Jay O. Cohen, PhD, U.S. Department of Health, Education and Welfare, Public Health Service, Bureau of State Services, Communicable Disease Center.

Am J Dis Child. 1963;105(6):689-691. doi:10.1001/archpedi.1963.02080040691020

A recent approach to the control of staphylococcal problems in hospital nurseries involves the implantation of a penicillin-sensitive staphylococcus (the 502A strain) in infants in an effort to interfere with colonization by more virulent organisms.1,2 The evaluation of the results of such implantation experiments depends upon accurate and definitive identification of the implanted strain and the ability to differentiate it from other strains of coagulase-positive staphylococci found in the environment. The use of two or more distinct typing systems, especially for cultures from lesions and other infections, greatly improves the reliability of the experiment. Toward this end selected representative staphylococcus strains from the Georgia study 2 were referred to the research laboratory for special serological and phage studies.

Materials and Methods  The serological system used in this study was developed by Oeding 3-5 and by Haukenes and Oeding.6 Methods of producing reagents and performing the tests are described