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November 1963

Hemodialysis in Infantile Nephrotic Syndrome: A Case Report Describing a New Hemodialysis System

Author Affiliations

Colin M. Walker, MD, Department of Pediatrics and Renal Service, University of Colorado Medical Center, 4200 E Ninth Ave, Denver 20.; Assistant Professor of Pediatrics, Pediatric Cardiology (Dr. Walker); Instructor, Department of Pediatrics (Dr. Wershing); Consultant Engineer (Mr. Simons); Professor of Medicine (Dr. Holmes); Fellow, Division of Renal Disease (Dr. Sitprija); Associate Professor of Pediatrics (Dr. O'Brien).; From the Department of Pediatrics and Renal Service, University of Colorado Medical Center.

Am J Dis Child. 1963;106(5):479-483. doi:10.1001/archpedi.1963.02080050481015

The application of hemodialysis for the treatment of renal failure in the older child is fairly extensive 1-6 and has been recently reviewed by Clapp et al.7 The literature contains reports of infants aged 4 months, 11½ months,9 and 7 months10 who have been treated successfully by hemodialysis. To date only peritoneal dialysis to remove bilirubin 8 has been reported in infants under three months of age. The development of a control system for the oxygenation of infants by extracorporeal perfusion 11 has been modified for the hemodialysis of such small infants. This report briefly describes the successful hemodialysis of a six-week-old infant with congenital nephrosis together with data from preparatory animal experiments.

Report of Case  A six-week-old female infant was admitted with a three-week history of swelling around the eyes and pitting edema in the legs.After a third-trimester toxemia the infant, weighing 3,100 gm (6⅞

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