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May 1964


Am J Dis Child. 1964;107(5):537. doi:10.1001/archpedi.1964.02080060539020

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To the Editor: I should like to comment in regard to the recent article (Amer J Dis Child 106:492, 1963) by Philip Vandeman entitled "Termination of Dietary Treatment for Phenylketonuria."

In my opinion, this report does not present adequate evidence to warrant discontinuance of the low phenylalanine diet in phenylketonuric children. In case 1 therapy was stopped in spite of the fact that at age 34½ months the youngster exhibited nearly normal development as compared to Gesell norms. Only in speech activities and toilet training was the subject behind. Perhaps if dietary therapy had been continued his IQ at 58 months would have been significantly higher. Our clinical impression would support this conclusion. The fact that the IQ ranged from 67 to 74 from age 58 to 88 months is not sufficient to conclude that his IQ at 10 or 15 years of age will be in the same range.

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