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June 1964

On the Early Onset of Ophthalmoplegic Migraine

Author Affiliations

Frederick Anderman, MD, The Montreal Children's Hospital, 2300 Tupper St, Montreal 25, Quebec, Canada.; From the Department of Neurology and Neurosurgery, McGill University, and The Department of Neurology, The Montreal Children's Hospital.

Am J Dis Child. 1964;107(6):628-631. doi:10.1001/archpedi.1964.02080060630013

"In Germany, where the first descriptions of this syndrome have originated, it is described as 'recurrent oculomotor paralysis' or 'periodic oculomotor paralysis.' I prefer to call it 'ophthalmoplegic migraine' mainly because, unless I am mistaken, it is a more graphic description, pointing out the un questionable analogies between the condition under scrutiny here and the classical mi graines; also because it highlights a feature which is not present in the other descrip tions, namely the element of pain which is a salient feature of this condition; in this form of migraine the oculomotor paralysis occurs as far as I am aware, only following a pe riod of pain most often accompanied by vomiting."

It is hard to improve on Charcot's mas terly description of the clinical syndrome of ophthalmoplegic migraine. It consists of at tacks of continuous severe headache localized to the eye or to the forehead and hemicranium