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December 1964

Dynamic Classification of Bone Dysplasias.

Am J Dis Child. 1964;108(6):701-702. doi:10.1001/archpedi.1964.02090010703024

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In 1959, Dr. Rubin reported alterations in growing bone resembling several skeletal dysplasias (loosely known as skeletal dystrophies) which he had produced experimentally by exposure to ionizing radiation. The present volume is a direct outgrowth of the ingenious experimentation and subsequent dissatisfaction with classifications of growth disorders of the skeleton into which were to be fitted his observations. The available classifications were based largely on morphologic (ie, static) features including distribution of lesions (local or generalized), possible sites of primary involvement (epiphysis, metaphysis, diaphysis), or possible types of primary skeletal formation affected (enchondral, periosteal, or both). Dr. Rubin now offers a new "dynamic" classification based on identification of several components of bone growth and development and their contributions to ultimate form—what Rubin calls "the logic of bone growth." The various dysplasias are analyzed with respect to specific deviations of individual components and categorized accordingly.

The functional components of tubular bones,

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