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March 1965

Urinary Tract Infection In Children: II. Identification of Escherichia Coli O Antibodies in Serum of Patients

Author Affiliations

From the Department of Pediatrics of the State University of New York at Buffalo and Children's Hospital.

Am J Dis Child. 1965;109(3):238-242. doi:10.1001/archpedi.1965.02090020240008

Introduction  RECENT studies have revealed that of the 140 serogroups (O groups) of Escherichia coli only nine account for 44% to 61% of urinary tract infection in children and adults.1-4 It has been shown, too, that a specific O antibody response to the infecting microorganism can be demonstrated in many of these patients.4-8 The hemagglutination test has been employed to this end, for this method has proved to be a sensitive tool for the detection and titration of a variety of antibodies, including O antibodies of E coli, Salmonella, Shigella, and others (see reference 9). The present study was carried out as part of a long-range investigation * of urinary tract infection of children to determine whether antibodies in the serum of patients produced in response to the infection can be utilized for the identification of the serogroups of the urinary strains of E coli.

Materials and Methods  Patients

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