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September 1965

Mima polymorpha Meningitis in the Young

Author Affiliations

From the departments of pathology and pediatrics, Presbyterian Hospital, and the University of Pennsylvania School of Medicine. Assistant Pathologist, Presbyterian Hospital, and Instructor in Pathology, University of Pennsylvania School of Medicine (Dr. Hermann). Assistant Pediatrician and Epidemiologist, Presbyterian Hospital, and Associate Professor of Pediatrics Emeritus, Graduate School of Medicine, University of Pennsylvania (Dr. Melnick).

Am J Dis Child. 1965;110(3):315-318. doi:10.1001/archpedi.1965.02090030329018

TWO AND ONE-HALF decades ago, DeBord1 encountered an apparently distinctive group of gram-negative diplococci which mimicked certain clinical and bacteriological features of Neisseria gonorrhoeae; he proposed that these agents be grouped into a tribe called Mimeae. Since then, increasing numbers of reports2-5 in the English literature have confirmed this tribe's etiologic role in a wide variety of primary clinical infections. Reports6-9 of Mima polymorpha meningitis have appeared sporadically since DeBord's10 first description, but recently sufficient cases have accumulated to outline a characteristic clinical picture. We report two instances of meningitis caused by M polymorpha, var. oxidans to call attention to their resemblance to meningococcal meningitis and to the possibility of central nervous system infection caused by the Mima-like organisms.

Report of Cases  Case 1.—AS, a 16-year-old white schoolboy, entered the hospital because of a severe headache. Well until eight days prior to admission, he developed

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