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December 1965

Blood Lactate in the Respiratory Distress Syndrome: Significance in Prognosis

Author Affiliations

From the Department of Pediatrics (Capt Graven and Col Holcomb) and Aerospace Medical Laboratory (Clinical) (Mr. Criscuolo), Wilford Hall, US Air Force Hospital, Aerospace Medical Division (AFSC), Lackland Air Force Base. Capt Graven is now at the Department of Pediatrics, University of Wisconsin, Madison, Wis.

Am J Dis Child. 1965;110(6):614-617. doi:10.1001/archpedi.1965.02090030642004

A NEED EXISTS for some measurement by which the prognosis of infants with respiratory distress syndrome (RDS) can be predicted early in the course of the disease. The concentration of lactate in the blood has been proposed as a determination which may have prognostic significance in RDS with increased concentrations occuring in the most severely involved infants.1,2 It is the purpose of this study to examine the prognostic value of lactate concentrations during the course of the RDS in premature infants.

Materials and Methods  The infants included in this study were born in the Wilford Hall, US Air Force Hospital between October 1963 and December 1964. The pediatric resident present at the deliveries resuscitated the infants and assigned the Apgar ratings. All infants were transferred as soon as possible to the intensive care nursery where they were weighed and placed in an isolette with full humidity and sufficient heat

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