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December 1965

Tolnaftate in Superficial Fungus Infections

Author Affiliations

From the Department of Pediatrics, University of California-San Francisco Medical Center, and St. Luke's Hospital and Children's Hospital, San Francisco.

Am J Dis Child. 1965;110(6):624-627. doi:10.1001/archpedi.1965.02090030652006

TOLNAFTATE, a pharmacologically inert new fungicide for topical treatment of superficial mycoses, has been reported to be highly effective in skin infections caused by common pathogenic fungi as well as being nonirritating and nonsensitizing.1,2

This paper reports our nine-month investigation on tolnaftate in the treatment of a variety of superficial fungus infections. Eleven of the 157 patients had dermatophytoses in multiple areas and the total number of sites studied was 168.

Procedure  The patients were from the Outpatient Clinics of the University of California-San Francisco Medical Center, Childrens' Hospital and St. Luke's Hospital (during 1963-64). Ninety of the 157 patients were in the 1- to 15-year age range. Infection had been present one month or less in 75 of the patients; 78 had infection for periods ranging from one month to one year, and 4 for two or more years. Eighteen patients had previous therapy which included hot soaks,

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