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December 1965

Varicella and Hypoglycemia With Recovery: Case Report

Author Affiliations

Dr. Nader is now at the Childhood Virus Disease Unit, Department of Health, Education, and Welfare, Communicable Disease Center, Atlanta.; From the Department of Pediatrics, University of California-San Francisco Medical Center, and the Department of Communicable Diseases, Children's Hospital, San Francisco.

Am J Dis Child. 1965;110(6):678-682. doi:10.1001/archpedi.1965.02090030706017

THE SIMULTANEOUS and unaccountable occurrence of hypoglycemia in varicella is extremely rare. Mortimer and Lepow1 reported four cases in young infants who succumbed in the acute phase of their illness, but they found no similar cases in their review of the literature.

We are reporting the first case of varicella and hypoglycemia with apparently complete recovery. We include the results of a laboratory investigation of the patient's carbohydrate metabolism in regard to some of the known causes of hypoglycemia.

Report of a Case  A 3-year-old, 33 lb (15 kg), white female child developed fever and a characteristic varicella rash on March 21, 1964. Two days later she vomited her lunch and all subsequent clear liquid feedings for about 12 to 15 hours. On March 24, at 3 am, she received an antiemetic suppository containing sodium pentobarbital (30 gm) and pyrilamine maleate (25 mg). Despite almost immediate defecation, the vomiting

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