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April 1966

Acute Otitis Media in Children: Bacteriological Findings in Middle Ear Fluid Obtained by Needle Aspiration

Author Affiliations

From the Pediatric Service, Thorndike Memorial Laboratory, and Second and Fourth (Harvard) Medical Services, Boston City Hospital; the Department of Pediatrics, Boston University School of Medicine; and the departments of pediatrics and medicine, Harvard Medical School, Boston. Drs. Feingold and Gellis are now at Tufts University School of Medicine and Boston Floating Hospital.

Am J Dis Child. 1966;111(4):361-365. doi:10.1001/archpedi.1966.02090070059005

ACUTE otitis media presents one of the most frequent and perplexing infectious disease problems facing the pediatrician. Therapy is usually empirical, since cultures of the nose and throat, when done, reflect the causative agent only imperfectly.1,2 Therefore, the present study was carried out in children with acute otitis media and bulging tympanic membranes in order to determine whether needle aspiration of fluid from the middle ear would provide more direct and reliable information about the causative organisms. The bacteriological results of cultures of the aspirated fluids and comparisons with those of the throat and nasopharynx are presented in this paper. The results of attempts to isolate viruses and Mycoplasma from these aspirated fluids are to be reported separately.3

Patients, Materials, and Methods  A total of 90 children, seen at the Boston City Hospital between July 1964 and April 1965, who presented the clinical features of acute otitis media

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