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April 1966

Thoracic Gas Volume in Infancy: Comparison of Lung Volumes of Infants and Adults

Author Affiliations

From the Children's Hospital of Michigan and Wayne State University School of Medicine, Detroit.

Am J Dis Child. 1966;111(4):393-399. doi:10.1001/archpedi.1966.02090070091012

NORMAL values for the end-expiratory thoracic gas volume (TGVr, measured by the plethysmographic method) are available for newborn infants1-4 as are values for its ventilated portion, the functional residual capacity (FRC), determined by dilutional methods. TGVr and FRC are considered to be the same in normal subjects. There appears to be only one recent study on the TGVr which attempts to fill the gap in time between the young infant and older child. Although the measurement of TGVr or FRC is of only limited value in the diagnosis of lung disease in infants, knowledge of the normal values for TGVr throughout the age range from birth to adulthood may aid our understanding of the geometric dimensions of the lung and its units and thus has mechanical significance. The TGVr of newborns is low when compared with adults on the basis of body surface

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