[Skip to Navigation]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 35.173.234.169. Please contact the publisher to request reinstatement.
Article
April 1966

Sex Precocity and Polyostotic Fibrous Dysplasia: Report of a Case in a Boy With Testicular Biopsy

Author Affiliations

BOSTON
From the Medical Service (Endocrine Unit), Massachusetts General Hospital, and the Department of Medicine, Harvard Medical School, Boston.

Am J Dis Child. 1966;111(4):426-429. doi:10.1001/archpedi.1966.02090070124020
Abstract

SEXUAL PRECOCITY occurs frequently in girls with Albright's syndrome (polyostotic fibrous dysplasia of bone), but there are only five unequivocal cases reported in the literature describing this feature in boys.1-5 Why it occurs at all in either sex is as yet unexplained. Examination of the gonads of patients who have presented sexual precocity has been carried out in only a few instances in prepubertal girls, and there has been no evidence of ovulation ever having occurred.6-8 In the cases of prepubertal boys with Albright's syndrome who have shown sexual precocity, there is still less information: there are no reports concerning histology of the testes. The finding of mature spermatozoa in the case reported here not only confirms the sex precocity but also places the patient in the more specific category of true precocious puberty.

Report of a Case  A boy, 2 years and 5 months of age, was

×