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July 1966

A New Neurocutaneous Syndrome

Author Affiliations

From the departments of pediatrics, University of Minnesota (Dr. Marden), and the St. Paul-Ramsey Hospital (Dr. Venters), St. Paul, Minn.

Am J Dis Child. 1966;112(1):79-81. doi:10.1001/archpedi.1966.02090100115018

IN 1963 Feuerstein and Mims reported two cases of a new neurocutaneous syndrome with linear nevus sebaceus, convulsions, and mental retardation.1 Two additional cases with this triad have now been observed.2,3 Recently, the authors have had the opportunity to study a child who has this new syndrome in a more severe form than has heretofore been described. The purpose of this paper is to further define this entity and to call attention to the wide spectrum of anomalies that may occur.

Report of a Case  The patient was the product of a 38-week gestation of an 18-year-old mother and a 29-year-old father. The pregnancy was complicated by vaginal bleeding in the fifth month, by slightly elevated blood pressure, and by some ankle edema in the eighth month. Furthermore, during the fourth month the mother developed vaginal molluscum contagiosum which was confirmed by biopsy, but was not treated. The

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