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July 1966

Teratocarcinoma of the Heart: Case Report and Review of Primary Cardiac Malignancies in Children

Author Affiliations

From the departments of pathology and pediatrics, University of Mississippi School of Medicine, Jackson, Miss.

Am J Dis Child. 1966;112(1):87-91. doi:10.1001/archpedi.1966.02090100123020

THIS ARTICLE is to report a very rare cardiac tumor and to review briefly primary cardiac malignancies in children.

There have been several comprehensive reviews of cardiac tumors.1-3 Secondary (metastatic) cardiac tumors are said to be 20 to 40 times as common as primary cardiac tumors. About three quarters of the primary tumors are benign, and half the benign tumors are myxomas. Three quarters of the myxomas originate in the left atium. Other benign tumors include rhabdomyomas (which some pathologists regard as a hamartoma and others as a form of glycogen storage disease), fibromas, hamartomas, angiomas, lipomas, etc. Up to 1960, 178 primary cardiac malignancies had been reported.4 These were mostly sarcomas of different types, with a tendency to involve the ventricles, and to occupy the right side of the heart. Malignant mesotheliomas, especially of the pericardium were also noted. In 1954, Bigelow et al5 reviewed primary

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