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December 1966

Successful Treatment of the Maladie des Tics: Gilles de la Tourette's Syndrome

Am J Dis Child. 1966;112(6):541-545. doi:10.1001/archpedi.1966.02090150085006

THE STRANGE syndrome of convulsive tic of childhood, widely known as the maladie de Gilles de la Tourette1 has long rested in the shadowy borderland between neurology and psychiatry. Devoid of specific causal antecedents or certain morphology, yet associated with a highly characteristic course, the disease is strongly influenced by emotional factors, but highly resistant to psychotherapy. With few exceptions, prognosis for cure or alleviation has been extremely poor, and treatment with a variety of psychiatric, somatic, and pharmacologic therapies has only occasionally yielded satisfactory results. Thus, of great interest to pediatricians are several reports appearing in the recent literature of extraordinary success in treating this syndrome with the butyrophenone, haloperidol.2-4 We have recently had the opportunity to confirm these reports, having achieved excellent results from the use of haloperidol (Haldol) on the symptoms of convulsive tic in a carefully studied patient. The patient in the case to