Denouement and Discussion
(Congenital Telangiectatic Erythema and Stunted Growth)
The three cardinal features of Bloom's syndrome are congenital telangiectatic erythema of the face, sensitivity to sunlight, and stunted growth. Areas involved are the cheeks, nose, margins of the eyelids, lips, forehead, and ears. Generally, the eruption appears as "erythematous telangiectatic spots" or plaques or patches of scattered macular red lesions. The sun usually causes exacerbation of the eruption. The dwarfism may be classified as primordial or genetic in type. There is no evidence of hypopituitarism. An important feature of the dwarfism is low birth weight with normal gestational age. Slow growth usually becomes manifest in the early months of life. During childhood these children have a slender build with a narrow fine-featured face. The head circumference is small. Other reported associated defects involve both ectodermal or mesodermal tissues. They include: lichen
GELLIS SS, FEINGOLD M, BLOOM D. Picture of the Month. Am J Dis Child. 1966;112(6):581–582. doi:10.1001/archpedi.1966.02090150125015
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: