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December 1966

Wegener's Granulomatosis: Report of a Case in a 13-Year-Old Girl

Author Affiliations

From the departments of pediatrics (Drs. Feldman and Gruezo) and pathology (Dr. Fink), The Coney Island Hospital affiliate of Maimonides Medical Center, Brooklyn, NY.

Am J Dis Child. 1966;112(6):587-592. doi:10.1001/archpedi.1966.02090150131018

WEGENER'S granulomatosis is a rare, invariably fatal, granulomatous disease of unknown course first described in 1936.1 It is characterized by granulomata in the upper and lower respiratory tract and generalized arteritis and glomerulitis.2 The following case is presented to point out that, despite its rarity, this condition can occur in the pediatric age group.

Report of a Case  A 13-year-old white girl was admitted to the pediatric service because of cough and persistent fever. She had complained of tiring easily for three to four months although she continued her usual activities. One month prior to admission, she had conjunctivitis and stomatitis that cleared in about a week. Two weeks later, she developed a dry cough and fever. Her physician prescribed penicillin (600,000 units intramuscularly) and tetracycline (250 mg three times daily). After 48 hours of apparent improvement, fever recurred and cough and weakness became more severe. Three days

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