RETROSPECTIVELY, that form of pemphigus which has come to be known by the eponym of Senear-Usher syndrome or more formally as pemphigus erythematosus,* was first presented by Ormsby and Mitchell1 as a case for diagnosis at a meeting of the Chicago Dermatological Society in 1921. In 1925, before the American Dermatological Association, Senear and Usher analyzed 11 similar cases and described the salient features of the condition which has since borne their names.2 Their original description was of a dermatosis involving chiefly or exclusively the head and trunk. The clinical picture embraced features of both lupus erythematosus and pemphigus. The lesions were present on the trunk, usually in the areas involved in seborrheic dermatitis; they were flaccid bullae that ruptured readily and, on their sites, developed scales and crusts that were thick and dry or greasy.
Since this original description, many articles have been written about the clinical
Petratos MA, Andrade R. Pemphigus Erythematosus: Report of a Case in a Child Less Than 6 Years of Age. Am J Dis Child. 1967;113(3):394–397. doi:10.1001/archpedi.1967.02090180154019
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.