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May 1967

Pneumocystis carinii Pneumonia in Congenital Rubella

Author Affiliations

From the departments of pathology (Drs. Lingeman and Schulz), and pediatrics (Dr. Lukemeyer), Indiana University School of Medicine, Indianapolis. Dr. Lingeman is now at the National Cancer Institute, National Institutes of Health, Bethesda, Md.

Am J Dis Child. 1967;113(5):585-587. doi:10.1001/archpedi.1967.02090200117014

THE VARIED clinical and pathologic manifestations of congenitally acquired and often continued postnatal infection by rubella virus have been described,1-4 although some of the pathologic processes have not been completely characterized. Many of the changes are reversible in infants who survive,2,3 although 20% to 30% succumb in the early weeks of life.1,2 The case reported is that of an infant in whom there was clinical, pathologic, and virologic evidence of congenital rubella and the unsuspected complication of interstitial plasma cell pneumonitis in which organisms characteristic of Pneumocystis carinii were observed.

Report of a Case  A 3-month-old Negro girl was referred to the Indiana University Medical Center on March 22, 1965, because of failure to gain weight, and cough and fever of three days duration.The infant was born on Dec 8, 1964, at term. Birthweight was 2,500 gm (5 lb 9 oz). Labor and delivery were uncomplicated.