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May 1967

A Pathological Model for Cerebral Changes Incident to Paranatal Anoxia: Report of a Case of Cerebral Atrophy Secondary to Cardiorespiratory Failure in Infancy

Author Affiliations

Los Angeles
From the Cajal Laboratory of Neuropathology, Department of Pathology, Los Angeles County Hospital, and the Department of Neurology, Loma Linda University, Los Angeles.

Am J Dis Child. 1967;113(5):603-610. doi:10.1001/archpedi.1967.02090200135020

IN RECENT years, attention has been called to the use of models of various sorts to account for the manifold phenomena in biology. Perhaps the most useful and available treatise on this subject is the publication of a symposium held in September 1959 by the Society for Experimental Biology. This symposium, edited by Beament,1 points out that models may have many applications in this field of study. They may be either mechanical or conceptual and used in evaluation or demonstration of biological phenomena. However, a common use of models of this sort has been in the classification of biological entities by the establishment of a certain species, and the determination of a type which is comparatively basic for the group as a whole.

The present writer has adapted this concept of a biological model in helping him to understand the relationship of several pathological entities on the basis of