This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.
The rapidity with which knowledge has accumulated regarding human chromosomes is remarkable. It is only ten years since the number of human chromosomes was accurately determined. In the ensuing decade there have been recognized numerous chromosomal abnormalities of interest to both the clinician and the cytogeneticist. Unfortunately the clinician, often bewildered by the technology and the jargon of cytogenetics, has frequently ignored developments in this highly specialized area. The author of this book has succeeded in communicating to the clinician, in his language, the significant developments in this field.
The book opens with a brief, perhaps too brief, description of cell morphology. This is followed by a more detailed account of normal and then abnormal cell division. There is then interjected an informative chapter on dermatoglyphics. The remaining two thirds of the book is devoted to the clinical disorders arising from abnormalities of the autosomes and sex chromosomes.
LIGHT IJ. The Chromosome Disorders: An Introduction for Clinicians. Am J Dis Child. 1967;113(5):628–629. doi:10.1001/archpedi.1967.02090200160025
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: