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August 1967

Drug Therapy for Epilepsy: Anti-Convulsant Drugs; Usage, Metabolism, and Untoward Reactions (Prevention, Detection, and Management).

Am J Dis Child. 1967;114(2):224-225. doi:10.1001/archpedi.1967.02090230154044

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


Livingston and his associates have made available to physicians and students the tremendous experience of the Johns Hopkins Hospital Epilepsy Clinic during the past 30 years. This involves the examination, treatment, and follow-up of over 16,000 patients of all ages. The Hopkins classification of seizures is well presented in a concise table. Another table lists most of the drugs, old and new, which have been used at the clinics. A third lists the costs. The anticonvulsant compounds in current use are described in concise detail with the history, efficacy, and reactions reported. The seven fatalities on diphenylhydantoin reported in the literature are presented and perhaps the toxic reactions of diphenylhydantoin in children should be emphasized.

A short chapter on the treatment of hypoglycemia by Allan L. Drash, MD, is concise and inclusive. The bibliography is complete.

This book contains literature the practicing physician or neurologist will need for clinical purposes.

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