Physical Features of Chinese Children With Down's Syndrome

DOWN'S SYNDROME has been found in all major races,^1-11 but there are few quantitative studies of clinical signs on groups other than whites. The occurrence of major malformations in Down's syndrome has been reviewed recently by Warkany, et al.¹² A previous report qualitatively discussed the physical findings in a series of 20 Chinese children with Down's syndrome,⁹ and some quantitative data are available for a series of 11 Japanese cases.⁵ Quantitative data are available for 29 cases of Oriental origin (Chinese, Japanese, and other) in Hawaii.⁴

The present article is a study of the frequency of previously described stigmata in a sample of 56 Chinese children with Down's syndrome born in the area of Taipei, Taiwan. It is one phase of a comprehensive investigation of Down's syndrome in Chinese. The other phases, including cytogenetics, dermatoglyphics, and epidemiology, will be reported elsewhere.

Report of Cases  Physical