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October 1968

Methanol Poisoning in an InfantSuccessful Treatment With Peritoneal Dialysis

Am J Dis Child. 1968;116(4):445-447. doi:10.1001/archpedi.1968.02100020449021

SINCE Marc-Aurele and Schreiner1 demonstrated the usefulness of hemodialysis in the therapy of methanol poisoning, this method of therapy has proved to be an effective means of removal of methanol and its metabolic products from patients with methanol intoxication.2 Peritoneal dialysis also has been utilized for the treatment of adult patients with methanol poisoning.3,4 To our knowledge, there have been no cases of methanol poisoning in infants or children which were treated with either peritoneal dialysis or hemodialysis. We wish to report the case of a 10-week-old infant who sustained severe methanol poisoning but recovered after treatment with intravenously administered bicarbonate and peritoneal dialysis.

Methods  Blood samples were obtained by venipuncture, placed in sealed tubes, and transported to the laboratory without delay. Methanol content was determined by the method of Harger,5 and aliquots of the same specimens were analyzed for methanol content by the gas chromatographic

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