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July 1969

Congenital RubellaLong-Term Follow-up Study

Am J Dis Child. 1969;118(1):32-34. doi:10.1001/archpedi.1969.02100040034006

SIR Norman Gregg died in Sydney in July 1966, almost exactly 25 years after the first presentation of his observations on congenital malformations following maternal rubella.1 As a tribute to this man and his work, and as a natural extension of recent observations of the long-term persistence of rubella virus2 and the postnatal development of cataracts3,4 in subjects with congenital rubella, it was decided to carry out a 25-year follow-up study of 50 of the first well-documented cases of this syndrome.5 The 50 patients were born in New South Wales between 1939 and 1944, comprised 22 male and 28 female subjects, and were included in the group on the basis that there appeared no reasonable doubt, in retrospect, of the clinical diagnosis of congenital rubella.5

The defects observed in these 50 patients are summarized in Table 1. Deafness was present in 48 cases, with cataract

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