[Skip to Navigation]
January 1970

Epidemiology of Mongolism.

Author Affiliations


Am J Dis Child. 1970;119(1):94. doi:10.1001/archpedi.1970.02100050096024

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


Epidemiology is the study of the distribution of a disease in a population and of the factors influencing this distribution. As a chronic disease with presumably many causes, mongolism (Down's syndrome) admirably lends itself to an epidemiologic critique. The Epidemiology of Mongolism is a provocative attempt to arrange the known factors of mongolism into statistical significant form from which to suggest research areas and etiologic hypotheses.

From the prolific literature of mongolism and within the early pages of this book, mongolism appears with such wide intragroup variability of physical and developmental characteristics that comparison of reports is often meaningless. The inconsistency of diagnostic criteria, record keeping, maternal characteristics, and chromosomal analysis leads to confusion. Dr. Lilienfeld counsels that allusive data can be consolidated when mongols are expressed in terms of their chromosomal type: nondisjunction, translocation, mosaic. He contemplates that variability in form is a differential effect of distinct etiologic agents

First Page Preview View Large
First page PDF preview
First page PDF preview
Add or change institution