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Article
March 1970

Multicystic Disease: Association With Congenital Cretinism and Infantile Diabetes

Author Affiliations

Chicago
From the departments of pediatrics (Drs. Melam and Traisman), and pathology (Drs. Kidd and Lipardo), Northwestern University Medical School, and Children's Memorial Hospital, Chicago.

Am J Dis Child. 1970;119(3):270-273. doi:10.1001/archpedi.1970.02100050272019
Abstract

Cystic disease of the kidney has previously been discussed and reported.1-3 Recent interest has centered on the association of cystic disease of the kidney and liver.4

The following is a report of a case of an infant who had cystic disease of the kidney and pancreas but not of the liver. In addition, the patient had clinical manifestations of hypothyroidism and diabetes mellitus before 1 year of age. While the association of diabetes mellitus with spontaneous hypothyroidism has been reported,5-9 it has not been documented before in an infant with multicystic organ disease.

Report of a Case  A white female infant was seen at Children's Memorial Hospital, Chicago, on Aug 27, 1966, at 3 months of age, with persistent jaundice and failure to gain weight. She was the product of an uncomplicated 40-week gestation and normal spontaneous delivery. At birth, the infant weighed 2 kg (4 lb)

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