[Skip to Navigation]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 18.207.129.82. Please contact the publisher to request reinstatement.
Article
April 1970

Development and BEI of Low-Birth-Weight Infants Full-Term and Through 18 Months

Author Affiliations

Providence, RI
From the Thyroid Laboratory, Providence Lying-In Hospital and Institute of Life Sciences, Brown University, Providence, RI.

Am J Dis Child. 1970;119(4):298-307. doi:10.1001/archpedi.1970.02100050300003
Abstract

Serum thyroxine-like iodine compounds (BEI) are essential for normal central nervous system development, but thyroid function tests of full-term and of low-birth-weight infants have not been defined through 18 postnatal months. For 49 full-term infants (normal BEI through five postnatal days 7.2μg to 15.2μg per 100 ml), median and mean BEI from two to six postnatal months were 6.2 ± 0.91 and from 6 to 18 months 5.8μg ± 0.87μg per 100 ml, significantly higher BEI values than for adults. Differences between BEI means of low-birth-weight infants born before and after 34 gestational weeks and of full-term infants were significant at the 0.001 level. Fifteen low-birth-weight infants with BEI determinations until 19 months were examined developmentally; nine, classified normal, appeared to have increasing BEI; six, classified suspect or abnormal, had low or borderline BEI.

×