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April 1970

Exomphalos-Macroglossia-Gigantism Syndrome in Jamaican Infants

Author Affiliations

Kingston, Jamaica
From the departments of pathology (Dr. Thorburn) and pediatrics (Dr. Miller), University of the West Indies, and Children's Hospital (Drs. Wright and Smith-Read), Kingston, Jamaica, West Indies.

Am J Dis Child. 1970;119(4):316-321. doi:10.1001/archpedi.1970.02100050318006

The clinical and laboratory findings in six Jamaican infants with the exomphalos-macroglossia-gigantism syndrome are described. The incidence was calculated as 1:13,700 births. There was no family history of similar disease in any case and no evidence of chromosomal abnormality, virus infection, or infantile hypoglycemia. Three infants died, and two showed typical histological features in the kidneys and adrenal glands.

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