A 41-year-old man presented with congenital hemihypertrophy. At 15 years of age, the patient developed bilateral varicose veins and lymphedema of the right leg. At age 20 years, he developed streptococcal cellulitis of the right leg and has had numerous similar episodes since, which frequently progress to septicemia. The long-term management of congenital hemihypertrophy must be concerned with the possible occurrence of childhood neoplasms, mental retardation, abnormal sexual development, and the complications of associated vascular anomalies.
Haicken BN. Congenital Hemihypertrophy: Problems in Long-Term Management. Am J Dis Child. 1970;120(4):372–373. doi:10.1001/archpedi.1970.02100090146022
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