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January 1971

"Arthrogryposis Multiplex Congenita" in One of Identical Twins

Am J Dis Child. 1971;121(1):64-66. doi:10.1001/archpedi.1971.02100120100016

One monozygotic twin is afflicted with arthrogryposis multiplex congenita. A review of the literature has revealed an apparently inconsistent pattern of transmission, conflicting views as to the primary site of involvement, a wide spectrum of variably associated congenital anomalies, and a postulated link with other identified neurologic disorders. We support the proposal that arthrogryposis is a sign present in several syndromes, probably of differing etiologies. Classification under this purely descriptive term should be avoided.