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April 1971

Myocarditis and Pneumonitis With Type 21 Adenovirus Infection: Association With Fatal Myocarditis and Pneumonitis

Author Affiliations

From the Division of Pathology, Presbyterian-St. Lukes Hospital, the departments of medicine and of preventive medicine and community health, Abraham Lincoln School of Medicine, University of Illinois at the Medical Center, and the Department of Virology, Hektoen Institute for Medical Research of the Cook County Hospital, Chicago. Dr. Henson was a Public Health Service special postdoctoral fellow. He is now with the Section on Infectious Diseases, Perinatal Research Branch, National Institute of Neurological Diseases and Stroke, Bethesda, Md.

Am J Dis Child. 1971;121(4):334-336. doi:10.1001/archpedi.1971.02100150108015

Adenovirus type 21 was isolated from the lungs of an 11-month-old infant who died of a nonsuppurative myocytolytic myocarditis with lesions present in both left and right ventricular myocardium, and a focal interstitial pneumonitis. Virus particles were not seen in heart muscle under the electron microscope. Other viral or bacterial pathogens were not isolated. Thus, it appears that adenovirus type 21 should be included in the group of viruses which, on occasion, are associated with fatal cardiorespiratory disease.

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