The diagnosis of systemic sclerosis in a 4-year-old girl was confirmed by histologic study. The patient, who has been followed-up for four years, has developed most grotesque features and now resembles a living mummy. This patient may represent the first reported juvenile case of diffuse scleroderma with severe extropion and exposure keratitis.
Velayos EE, Cohen BS. Progressive Systemic Sclerosis: Diagnosis at the Age of 4 Years. Am J Dis Child. 1972;123(1):57–60. doi:10.1001/archpedi.1972.02110070107016
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