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February 1972

A New Experimental Model of Polycystic Kidneys: Similarity to a Human Variety

Author Affiliations

Athens, Greece
From the Department of Pathology, Evangelismos Medical Center, Athens, Greece.

Am J Dis Child. 1972;123(2):118-120. doi:10.1001/archpedi.1972.02110080096007

The production of polycystic renal disease in newborn rabbits by the use of a long-acting corticosteroid, fluprednisolone (Predef 2x [Greece]; Alphadrol; comparable US product) as reported by Perey et al has been confirmed and extended. Rabbits followed up to 3 months of age show disappearance of the cysts. Comparison with "glomerular" type human polycystic kidney shows important similarities.