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March 1972

Mattenheimer's Clinical Enzymology: Principles and Applications.

Am J Dis Child. 1972;123(3):267. doi:10.1001/archpedi.1972.02110090137033

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The term "clinical enzymology" evidently refers in this instance to enzymology as practiced in the usual clinical laboratory. At the present time, this is generally limited to the measurement of enzyme activities in blood and their relation to heart and liver disease. The most effective parts of the book are devoted to these aspects. "Principles of enzymology and of cellular and tissue enzymology in the context of organ function provide the background for 'why and how' enzyme activities are determined in serum." Mattenheimer has concentrated on presenting this information for the physician, pathologist, clinical biochemist, and medical student.

It is a small book (168 pages) with a very broad scope. Among the ten chapter headings are: "Principles of Enzymology" (18 pages), "Main Pathways of Intermediary Metabolism" (14 pages), "Enzymes and Hormones" (5 pages), "Protein Synthesis and Biochemical Genetics" (6 pages), "Inborn Errors of Metabolism" (23 pages), "Enzymes in Blood Plasma"

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