Thirteen members of a family of 182 demonstrated laboratory or historical evidence of thrombocytopenia. The onset of bleeding symptoms occurred around the age of 6 years, followed by spontaneous remission of symptoms but not thrombocytopenia in early adult life. Treatment ranged from symptomatic care to long-term steroid therapy or splenectomy. The disorder is inherited in an X-linked recessive manner but appears to be distinct from the Wiskott-Aldrich syndrome in other respects.
Chiaro JJ, Dharmkrong-at A, Bloom GE. X-Linked Thrombocytopenic Purpura: I. Clinical and Genetic Studies of a Kindred. Am J Dis Child. 1972;123(6):565–568. doi:10.1001/archpedi.1972.02110120089008
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