[Skip to Navigation]
June 1972

Linear Sebaceous Nevus Syndrome: A Hamartoma Variant

Author Affiliations

Kansas City, Kan
From the departments of pediatrics (Drs. Lansky, Funderburk, Diehl, and Schimke) and pathology (Dr. Cuppage), University of Kansas School of Medicine, Kansas City.

Am J Dis Child. 1972;123(6):587-590. doi:10.1001/archpedi.1972.02110120111015

Three infants had linear sebaceous nevus syndrome. It is suggested that this syndrome be considered a hamartoma variant. In the first patient, postmortem examination of the kidneys revealed bilateral nodular nephroblastomatosis. Cortical blindness and intractable seizures were noted in the second patient. Cardiac involvement was present in two patients. Similarities between linear sebaceous nevus syndrome and tuberous sclerosis include involvement of numerous organ systems in addition to the skin and brain.

Add or change institution