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Article
July 1972

Measles Antibody in Previously Immunized Children: The Need for Revaccination

Author Affiliations

Cincinnati
From the Clinical Virology Section, Infectious Disease Division, Department of Medicine (Drs. Linnemann and Schiff) and Department of Pediatrics (Drs. Dine and Bloom), College of Medicine, University of Cincinnati.

Am J Dis Child. 1972;124(1):53-57. doi:10.1001/archpedi.1972.02110130055008
Abstract

Measles antibody was measured in three groups of children: (1) those who had received live measles virus vaccine at less than 1 year of age, (2) previously immunized siblings of children with clinical measles at the time of this study, and (3) previously immunized children who were revaccinated with live further attenuated measles virus vaccine. The results of this study indicated that children who have received live measles virus vaccine at less than 1 year of age, particularly less than 11 months, have very low antibody levels and may need revaccination. This can be accomplished in many children with the live further attenuated measles virus vaccine. However, following exposure to natural measles, many previously immunized children will experience a natural boost in titer.

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