Peripheral joint imaging is a useful tool in evaluation of children with peripheral bone or joint disease since it is simple and associated with a low radiation dose. The pattern of isotope localization provides the clinician with documentation of synovitis in order that he may follow the course of an illness or, in some instances, have an aid in differential diagnosis.
Peripheral joint imaging has been used as an aid in early diagnosis of bone or joint infection. Changes appearing in imaging have antedated radiographic changes by up to one week.
A characteristic pattern of isotope localization is seen in the epiphyseal area of normal joints; however, normal localization may be obscured in some children with inflammatory joint conditions because of the intense isotope localization in the diseased joint. The finding of decreased epiphyseal localization in children receiving large doses of prednisone may be a related factor in their poor growth response.
Shuler SE, Aprill CN, Weiss TE. Peripheral Joint Imaging: Method of Evaluation of Pediatric Bone or Joint Disease. Am J Dis Child. 1972;124(5):673–678. doi:10.1001/archpedi.1972.02110170051007
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