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March 1973

Massive Intracranial Hemorrhage in Sickle-Cell Anemia

Author Affiliations

Brooklyn, NY
From the departments of pediatrics (Drs. Falter and Robinson) and pathology (Dr. Sutton), State University of New York, Downstate Medical Center, and State University-Kings County Hospital Center, Brooklyn, NY 11203 (Dr. Falter).

Am J Dis Child. 1973;125(3):415-416. doi:10.1001/archpedi.1973.04160030073015

A 61/2-year-old black boy known to have sickle-cell anemia died shortly after developing sudden lethargy which progressed into unconsciousness. Bloodless spinal fluid suggested a diagnosis of cerebral thrombosis, but the postmortem examination revealed a massive subdural hemorrhage to be the cause of death. Although it is a rare complication, massive intracranial hemorrhage should be considered in the differential diagnosis in a child with sickle-cell anemia who shows acute neurological signs.