The features of the Cornelia de Lange syndrome were seen in a newborn whose older sibling had died two weeks after birth with multiple congenital abnormalities. A review of available data on the older sibling documented that this baby had a condition compatible with the Cornelia de Lange syndrome.
This is the fifth report of two children affected with the Brachmann-de Lange syndrome in a sibship. This report stresses the importance of exact history taking in a situation where a disease with possible genetic implications exists.
Lieber E, Glaser JH, Jhaveri R. Brachmann-de Lange Syndrome: Report of Two Cases in a Sibship. Am J Dis Child. 1973;125(5):717–718. doi:10.1001/archpedi.1973.04160050065013
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