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June 1973

Studies in Children With Impetigo: Bacteriology, Serology, and Incidence of Glomerulonephritis

Author Affiliations

From the departments of medicine (Dr. Hall) and pediatrics (Dr. Blumberg), Emory University School of Medicine; Pediatric Service, Grady Memorial Hospital; and the Center for Disease Control Health Services and Mental Health Administration (Dr. Moody), Public Health Service, US Department of Health, Education, and Welfare, Atlanta.

Am J Dis Child. 1973;125(6):800-806. doi:10.1001/archpedi.1973.04160060014003

One hundred fifty children with impetigo were studied over a two-year period. Group A β-hemolytic streptococci were isolated from the skin lesions of the majority (75%) of patients. The streptococcal pyoderma strains were further classified by agglutination reactions with T-antisera, the most frequent patterns being 25/Imp.19, T-12, and 3/B3264. No predominant staphylococcal pyoderma strains were noted by phage typing.

Treatment with cleansing and local application of antibiotics were effective in healing the lesions within one to three weeks. Follow-up clinical examination and urinalyses revealed one patient who developed significant hematuria of acute glomerulonephritis, an attack rate of approximately 1%.