A 14-year-old girl with a vitamin D-poor diet and receiving phenobarbital for epilepsy developed florid rickets. After being cured of this, and while on a maintenance dose of vitamin D, the addition of diphenylhydantoin sodium was accompanied by a recurrence of the rickets, which was corrected by raising the dosage of vitamin D from 600 to 1,200 international units per day.
Teotia M, Teotia SPS. Rickets Precipitated by Anticonvulsant Drugs: In a Child Receiving Prophylactic Vitamin D. Am J Dis Child. 1973;125(6):850–852. doi:10.1001/archpedi.1973.04160060056012
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