Nine of 1,152 liveborn infants had a single umbilical artery detected shortly after birth (four in the delivery room and five by routine umbilical cord sectioning on the following morning). One had multiple obvious congenital anomalies and died shortly after birth. All nine were investigated by chromosome analysis. Five were studied by trans-umbilical artery aortography and pyelography without showing any abdominal aorta or renal abnormalities.
The eight survivors were examined clinically (for 1 to 15 months) for evidence of unilateral shortening of a lower extremity and none was detected.
Johnsonbaugh RE. Unilateral Short Lower Extremity and Single Umbilical Artery: Absence of a Relationship. Am J Dis Child. 1973;126(2):186–187. doi:https://doi.org/10.1001/archpedi.1973.02110190164010
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