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June 1974

The Russell-Silver Syndrome

Author Affiliations

Southern California Permanente Medical Group 1050 W Pacific Coast Hwy Harbor City, CA 90710

Am J Dis Child. 1974;127(6):911. doi:10.1001/archpedi.1974.02110250137031

To the Editor.—In the December issue of the Journal (126:794, 1973), McDowell and Sproles state that "little has been published on the long-range follow-up of patients with this syndrome, particularly with reference to sexual development and intellectual capabilities in the older child." Minimal pertinent data are recorded on my own patient (case 2) published over ten years ago1; at that time he was 18 years old, mentally retarded, and dwarfed. So far as I could ascertain retrospectively from his clinic records, puberty had apparently been normal. However, his social adjustment was unsatisfactory.

My patient's experience differs from that reported by McDowell and Sproles and from that of Rimoin.2 Therefore, perhaps we are not describing the same syndrome; but this is a subject that I have touched on previously.3,4

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