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January 1975

Neonatal Haemophilus influenzae Infection: Report of Eight Cases and Review of the Literature

Author Affiliations

From the Department of Pediatrics, University of Colorado Medical Center, Denver.

Am J Dis Child. 1975;129(1):57-62. doi:10.1001/archpedi.1975.02120380037009

Eight cases of neonatal Haemophilus influenzae infection occurred at Colorado General Hospital during a 3½-year period. Four of the cases were due to nontypable organisms and four to type b organisms. Four were bacteremic, only two of which were type b. None of the patients had meningitis. In all instances, maternal genital tract cultures yielded H influenzae that, when tested, was of the same serotype as the infant isolate. A survey of cervical cultures among normal and pregnant women yielded H influenzae in less than 1%. There are several possible reasons for the disparity between the apparent high incidence of neonatal infection and low prevalence of maternal carriage.

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