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January 1975

Systemic Lupus Erythematosus in a 1-Year-Old Child

Author Affiliations

From the Albany (NY) Medical Center (Dr. Grossman), and the departments of pediatrics (Dr. Schwartz) and medicine (Drs. Callerame and Condemi), University of Rochester (NY), School of Medicine and Dentistry.

Am J Dis Child. 1975;129(1):123-125. doi:10.1001/archpedi.1975.02120380093022

An 11-month-old girl had systemic lupus erythematosus with a widespread skin rash. She manifested five of the criteria necessary for the diagnosis: oral ulcerations, alopecia, positive lupus erythematosus preparations, convulsions, and thrombocytopenia with leukopenia. Direct immunofluorescence showed deposits of IgG and C3 at the dermoepidermal junction of both abnormal and clinically uninvolved skin, and in subepithelial deposits along the glomerular basement membrane.

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