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May 1975

Severe Haemophilus influenzae Infections: Spectrum of Disease

Author Affiliations

From the departments of pediatrics, Children's Hospital of Denver (Dr. Todd), University of Colorado Medical Center (Drs. Todd and Bruhn), and Denver General Hospital (Dr. Bruhn).

Am J Dis Child. 1975;129(5):607-611. doi:10.1001/archpedi.1975.02120420047016

From May 1973 through April 1974, a total of 83 children with severe Haemophilus influenzae infections were treated in three Denver pediatric hospitals. Although meningitis was the most common clinical manifestation (45 cases), other foci of infection were also noted (pneumonia, 12 cases; cheek cellulitis, eight cases; epiglottitis, eight cases; empyema, seven cases; pericarditis, three cases; arthritis, one case; periorbital cellulitis, one case; and abscess, one case). Nine children had positive blood cultures with H influenzae without an initial detectable focus of infection. Two patients developed clinically apparent sites of infection (osteomyelitis and scalp abscesses).

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